Description
Recombinant mtTFA Monoclonal Antibody | E-AB-81584 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human
Host: Rabbit
Isotype: IgG
Application: WB, IHC-P, IF
Research Area: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction, Tags and Cell Markers
Background: This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants. TFAM (Transcription Factor A, Mitochondrial) is a Protein Coding gene. Diseases associated with TFAM include Mitochondrial Dna Depletion Syndrome 15, Hepatocerebral Type and Skin Carcinoma In Situ. Among its related pathways are Mitochondrial Gene Expression and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. GO annotations related to this gene include poly(A) RNA binding and chromatin binding.
Lead Time: 7~10 days
Concentration: 300 μg/mL
Storage: Store at -20℃. Avoid freeze / thaw cycles.
Immunogen: N/A
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Purification: Affinity Purified
Dilution: WB 1:1000-1:2000 IHC 1:50-1:100 IF 1:50-1:100
Conjugation: Unconjugated
Calculated Molecular Weight: 29kDa
Observed Molecular Weight: 24kDa
Clonality: Rabbit Monoclonal
