Description
Recombinant Mouse VCAM1 Protein (Fc Tag) | PKSM041260 | Gentaur US, UK & Europe Disrtribition
Synonyms: CD106;Vascular cell adhesion protein 1; Vcam1; L1CAM;VCMA1;Vcam-1
Active Protein: N/A
Activity: Recombinant Mouse VCAM-1 is produced by our Mammalian expression system and the target gene encoding Phe25-Glu698 is expressed with a Fc tag at the C-terminus.
Protein Construction: Recombinant Mouse VCAM-1 is produced by our Mammalian expression system and the target gene encoding Phe25-Glu698 is expressed with a Fc tag at the C-terminus.
Fusion Tag: C-Fc
Species: Mouse
Expressed Host: Human Cells
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 90 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per μg as determined by the LAL method.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 101.4 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Reconstitution: Please refer to the printed manual for detailed information.
Background: Vascular cell adhesion molecule 1 (VCAM-1) is a cell surface protein belonging to the immunoglobulin superfamily, the protein is expressed by activated endothelial cells and certain leukocytes (such as macrophages). IL-1 beta, IL-4, TNF-alpha and IFN-gamma induced the expression of VCAM-1. The human and mouse VCAM-1 proteins share approximately 76% amino acid similarity. Mouse VCAM-1 is Important in cell-cell recognition. it appears to function in leukocyte-endothelial cell adhesion, and interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction.
Research Area: N/A