Description
Recombinant Mouse TROP2/TACSTD2 Protein (His Tag) | PKSM041262 | Gentaur US, UK & Europe Disrtribition
Synonyms: Tumor-associated calcium signal transducer 2;Tacstd2;Trop2;Cell surface glycoprotein Trop-2; TROP-2;C80403;EGP-1;GA733-1;Ly97
Active Protein: N/A
Activity: Recombinant Mouse TROP2 is produced by our Mammalian expression system and the target gene encoding Gln25-Gly270 is expressed with a 6His tag at the C-terminus.
Protein Construction: Recombinant Mouse TROP2 is produced by our Mammalian expression system and the target gene encoding Gln25-Gly270 is expressed with a 6His tag at the C-terminus.
Fusion Tag: C-His
Species: Mouse
Expressed Host: Human Cells
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per μg as determined by the LAL method.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 28.8 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution: Please refer to the printed manual for detailed information.
Background: Tumor-associated calcium signal transducer 2(Tacstd2), also known as Cell surface glycoprotein Trop-2, belongs to the EPCAM family. Tacstd2 expressed in kidney, lung, ovary and testis and has high levels of expression in immortalized keratinocytes. Tacstd2 may functions as a growth factor receptor. It has negative regulation of branching involved in ureteric bud morphogenesis, cell motility, epithelial cell migration, ruffle assembly, stress fiber assembly and substrate adhesion-dependent cell spreading. Also, it has positive regulation of stem cell proliferation. Tacstd2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions.
Research Area: N/A