Description
Recombinant Mouse TIMP1 Protein (His Tag) | PKSM041388 | Gentaur US, UK & Europe Disrtribition
Synonyms: Metalloproteinase inhibitor 1;Collagenase inhibitor 16C8 fibroblast;Erythroid-potentiating activity;EPA;TPA-S1;TPA-induced protein;Tissue inhibitor of metalloproteinases 1;TIMP-1;Timp; Timp-1
Active Protein: N/A
Activity: A DNA sequence encoding the Mouse TIMP1 (P12032-1) (Pro28-Arg205) was expressed with a polyhistidine tag at the N-terminus.
Protein Construction: A DNA sequence encoding the Mouse TIMP1 (P12032-1) (Pro28-Arg205) was expressed with a polyhistidine tag at the N-terminus.
Fusion Tag: N-His
Species: Mouse
Expressed Host: E.coli
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 80 % as determined by reducing SDS-PAGE.
Endotoxin: Please contact us for more information.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 19.88 kDa
Formulation: Lyophilized from sterile PBS, pH 7.4
Reconstitution: Please refer to the printed manual for detailed information.
Background: Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14 (By similarity). Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling.
Research Area: N/A
