Description
Recombinant Mouse Semaphorin-4C/SEMA4C Protein (Fc Tag) | PKSM041138 | Gentaur US, UK & Europe Disrtribition
Synonyms: Semaphorin-4C;Semaphorin I;S4c; Semacl1; Semai;Sema I;Semaphorin-C-like 1;M-Sema F;Sema4c
Active Protein: N/A
Activity: Recombinant Mouse Semaphorin 4C is produced by our Mammalian expression system and the target gene encoding Ala21-Gly664 is expressed with a Fc tag at the C-terminus.
Protein Construction: Recombinant Mouse Semaphorin 4C is produced by our Mammalian expression system and the target gene encoding Ala21-Gly664 is expressed with a Fc tag at the C-terminus.
Fusion Tag: C-Fc
Species: Mouse
Expressed Host: Human Cells
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per μg as determined by the LAL method.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 99.3 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Reconstitution: Please refer to the printed manual for detailed information.
Background: Semaphorin-4C is a protein which belongs to the semaphorin family, contains 1 Ig-like C2-type domain, 1 PSI domain, 1 Sema domain. As cell surface receptor for PLXNB2, it plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. It required for normal brain development, axon guidance and cell migration, Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.
Research Area: N/A
