Recombinant Mouse SDF2 Protein (His Tag) | PKSM040783

Recombinant Mouse SDF2 Protein (His Tag) | PKSM040783 | Gentaur US, UK & Europe Disrtribition

Synonyms: AI853825

Active Protein: N/A

Activity: A DNA sequence encoding the mouse SDF2 (Q9DCT5) (Met 1-Leu 211) was expressed，with a C-terminal polyhistidine tag.

Protein Construction: A DNA sequence encoding the mouse SDF2 (Q9DCT5) (Met 1-Leu 211) was expressed，with a C-terminal polyhistidine tag.

Fusion Tag: C-His

Species: Mouse

Expressed Host: Baculovirus-Insect Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 90 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 22.8 kDa

Formulation: Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 8.0

Reconstitution: Please refer to the printed manual for detailed information.

Background: Stromal derived factors (SDFs) are a loosely defined group of molecules that are generated by stromal cells. Two of the stromal derived factors, SDF-1 and SDF-4 belong to the chemokine family. Other SDFs, such as SDF-2 and SDF-5 are not well defined and their biological functions are less known. SDF-2 is first isolated from the mouse stromal cell line ST2 as a secretory protein. The amino acid sequence deduced from the murine clone and the human homolog are conserved more than 92 %, and the aa sequence of SDF-2 shows similarity to those of yeast dolichyl phosphate-D-mannose, protein mannosyltransferases. SDF-1 and its receptor are strongly indicated in the progression of various cancers including breast cancer. SDF-2, SDF2-L1, SDF-4, and SDF-5 are ubiquitously expressed in various cancer cell lines and SDF-2, SDF-4 and SDF-5 are expressed in mammary tissues. These SDFs have prognostic value and warrant further investigation in their biological functions and clinical value.

Research Area: N/A