Description
Recombinant Mouse PSGL-1/CD162 Protein (aa 42-307, Fc Tag) | PKSM041283 | Gentaur US, UK & Europe Disrtribition
Synonyms: CD162;Psgl-1;Psgl1;Selp1;CLA; PSGL1; PSGL-1
Active Protein: N/A
Activity: Recombinant Mouse PSGL-1 is produced by our Mammalian expression system and the target gene encoding Gln42-Cys307 is expressed with a Fc tag at the C-terminus.
Protein Construction: Recombinant Mouse PSGL-1 is produced by our Mammalian expression system and the target gene encoding Gln42-Cys307 is expressed with a Fc tag at the C-terminus.
Fusion Tag: C-Fc
Species: Mouse
Expressed Host: Human Cells
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per μg as determined by the LAL method.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 54.7 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.
Reconstitution: Please refer to the printed manual for detailed information.
Background: P-selectin glycoprotein ligand 1 is the high affinitycounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. As such, it plays a critical role in the tethering of these cells to activated platelets or endothelia expressing P-selectin. As cell adhesion molecules, multiple studies have shown that PSGL-1/ P-selectin interaction is required for the normal recruitment of leukocytes during inflammatory reactions, and also participates in hemostatic responses. PSGL-1 can also bind to other two members of the selectin family, E-selectin (endothelial) and L-selectin (leukocyte), but binds best to P-selectin.
Research Area: N/A
