Recombinant Mouse Peroxiredoxin 5/PRDX5 Protein (His Tag)(Active) | PKSM040619

Recombinant Mouse Peroxiredoxin 5/PRDX5 Protein (His Tag)(Active) | PKSM040619 | Gentaur US, UK & Europe Disrtribition

Synonyms: AOEB166;AOPP;Pmp20;Prdx6;PrxV

Active Protein: Active protein

Activity: A DNA sequence encoding the mouse PRDX5 (mitochondrial) (P99029-1) (Met 49-Leu 210) was expressed, with a polyhistide tag at the N-terminus.

Protein Construction: A DNA sequence encoding the mouse PRDX5 (mitochondrial) (P99029-1) (Met 49-Leu 210) was expressed, with a polyhistide tag at the N-terminus.

Fusion Tag: N-His

Species: Mouse

Expressed Host: E.coli

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 92 % as determined by reducing SDS-PAGE.

Endotoxin: Please contact us for more information.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 18.5 kDa

Formulation: Lyophilized from sterile PBS, pH 7.5

Reconstitution: Please refer to the printed manual for detailed information.

Background: Peroxiredoxin-5, also known as Alu corepressor 1, Antioxidant enzyme B166, Liver tissue 2D-page spot 71B, Peroxisomal antioxidant enzyme, Thioredoxin peroxidase PMP20, Thioredoxin reductase, PRDX5 and ACR1, is cytoplasm protein which belongs to the?peroxiredoxin 2 family. Peroxiredoxin-5 / PRDX5 reduces hydrogen peroxide and alkyl hydroperoxides with reducing equivalents provided through the thioredoxin system. Peroxiredoxin-5 / PRDX5 is involved in intracellular redox signaling. The Peroxiredoxins / Prx are a family of 25 kDa peroxidases that can reduce H2O2 using an electron from thioredoxin (Trx) or other substances. The mammalian Peroxiredoxins / Prx family is divided into six groups ( PRDX1，PRDX2, PRDX3, PRDX4, PRDX5, PRDX6 ) on the basis of homology of amino acid sequences. They are located in the cytosol and play a role in the cell signaling system. All six mammalian peroxiredoxins are expressed in the lung. Peroxiredoxins / Prx is overexpressed in breast cancer tissues to a great extent suggesting that Peroxiredoxins / Prx has a proliferative effect and may be related to cancer development or progression.

Research Area: N/A