Description
Recombinant Mouse IMPAD1/IMP3 Protein (His Tag) | PKSM041326 | Gentaur US, UK & Europe Disrtribition
Synonyms: Inositol monophosphatase 3; Impad1; IMPA3
Active Protein: N/A
Activity: Recombinant Mouse IMPAD1 is produced by our Mammalian expression system and the target gene encoding Glu51-His356 is expressed with a 6His tag at the N-terminus.
Protein Construction: Recombinant Mouse IMPAD1 is produced by our Mammalian expression system and the target gene encoding Glu51-His356 is expressed with a 6His tag at the N-terminus.
Fusion Tag: N-His
Species: Mouse
Expressed Host: Human Cells
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per μg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 34.3 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, 10%Glycerol, pH8.0.
Reconstitution: Not Applicable
Background: IMPAD1 protein (IMPA3, gPAPP or IMPase 3) belongs to the inositol monophosphatase family. It is found in Purkinje cells, brain stem, lung and chondrocytes. Mouse IMPAD1 gene encodes a type II transmembrane Golgi-embedded glycoprotein with 356 amino acid residues which generates a 306 amino acid residues mature protein after processing. It is expressed in embryo, and in theory may catalyze myo-inositol monophosphate to myo-inositol. Free myo-inositol is used to generate inositol phospholipid, an essential component of intracellular signaling pathways that mobilize calcium. Mouse IMPAD1 exhibits 91% sequence identity with the human homologue.
Research Area: N/A