Description
Recombinant Mouse IL13RA1 Protein (Fc Tag) | PKSM041321 | Gentaur US, UK & Europe Disrtribition
Synonyms: Interleukin-13 receptor subunit alpha-1;IL-13RA1;Interleukin-13-binding protein;Novel cytokine receptor 4;NR4;CD213a1; IL-13 R alpha 1
Active Protein: N/A
Activity: Recombinant Mouse IL-13RA is produced by our Mammalian expression system and the target gene encoding Ala25-Thr340 is expressed with a Fc tag at the C-terminus.
Protein Construction: Recombinant Mouse IL-13RA is produced by our Mammalian expression system and the target gene encoding Ala25-Thr340 is expressed with a Fc tag at the C-terminus.
Fusion Tag: C-Fc
Species: Mouse
Expressed Host: Human Cells
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per μg as determined by the LAL method.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 63 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution: Please refer to the printed manual for detailed information.
Background: Interleukin-13 receptor subunit alpha-1(IL-13RA1), also known as NR4, belongs to the hemopoietin receptor family. Interleukin-13 receptor is a complex of IL4R, IL13RA1, and possibly other components. It interacts with TRAF3IP1 and binds with low affinity to interleukin-13(IL3). IL-13RA1, together with IL4RA, can form a functional receptor for IL13. It also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. The WSXWS motif in domains appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
Research Area: N/A
