Description
Recombinant Mouse ICAM-2/CD102 Protein (Fc Tag) | PKSM041208 | Gentaur US, UK & Europe Disrtribition
Synonyms: Intercellular adhesion molecule 2; Icam2; ICAM-2; Lymphocyte function-associated AG-1 counter-receptor; CD102; Icam-2; CD102 antigen;Ly-60
Active Protein: N/A
Activity: Recombinant Mouse Intercellular adhesion molecule 2 is produced by our Mammalian expression system and the target gene encoding Lys23-Gln222 is expressed with a Fc tag at the C-terminus.
Protein Construction: Recombinant Mouse Intercellular adhesion molecule 2 is produced by our Mammalian expression system and the target gene encoding Lys23-Gln222 is expressed with a Fc tag at the C-terminus.
Fusion Tag: C-Fc
Species: Mouse
Expressed Host: Human Cells
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per μg as determined by the LAL method.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 49.7 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, pH8.0.
Reconstitution: Please refer to the printed manual for detailed information.
Background: ICAM-2 is a 55-65 kD transmembrane glycoprotein possessing 2 extracellular Ig domains, a single transmembrane domain, and a short 26-amino acid cytoplasmic domain. ICAM-2 is expressed on most leukocytes, and is strongly expressed on vascular endothelial cells. Interactions of ICAM-2 and the integrin receptors mediate cell adhesion in a wide range of lymphocyte, monocyte, natural killer cell, and granulocytewith other cells, and play important roles in many adhesion-dependent immune and inflammation responses, such as T cell aggregation, NK-cell cytotoxicity and migration, lymphocyte recirculation, etc. Serum levels of ICAM-2 correlated significantly with the inflammatory and course sequences of trichinosis in mice and had a similar relation with blood eosinophilia. So, estimation of ICAM-2 serum levels may prove useful in diagnosis of trichinosis recent infections, and in monitoring the prognosis and response to treatment.
Research Area: N/A
