Description
Recombinant Mouse HGF Protein (His Tag) | PKSM041332 | Gentaur US, UK & Europe Disrtribition
Synonyms: Hepatopoietin-A; Scatter factor; SF; Deafnes; Autosomal recessive 39; DFNB39;F-TCF; Hepatocyte growth factor
Active Protein: N/A
Activity: Recombinant Mouse HGF is produced by our Mammalian expression system and the target gene encoding Gln33-Leu728 is expressed with a 6His tag at the C-terminus.
Protein Construction: Recombinant Mouse HGF is produced by our Mammalian expression system and the target gene encoding Gln33-Leu728 is expressed with a 6His tag at the C-terminus.
Fusion Tag: C-His
Species: Mouse
Expressed Host: Human Cells
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per μg as determined by the LAL method.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 80.4 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution: Please refer to the printed manual for detailed information.
Background: HGF, is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases. Mouse HGF is secreted as an inactive 728 amino acid (aa) single chain propeptide. It is cleaved after the fourth Kringle domain by a serine protease to form bioactive disulfide-linked HGF with a 60 kDa alpha and 30 kDa beta chain. HGF binds heparan-sulfate proteoglycans and the widely expressed receptor tyrosine kinase, HGF R/c-MET. HGF regulates epithelial morphogenesis by inducing cell scattering and branching tubulogenesis. It can also alter epithelium morphology by the induction of nectin-1 alpha ectodomain shedding, an adhesion protein component of adherens junctions.
Research Area: N/A
