Recombinant Mouse GSTM1 Protein (His Tag) | PKSM041382

Recombinant Mouse GSTM1 Protein (His Tag) | PKSM041382 | Gentaur US, UK & Europe Disrtribition

Synonyms: Glutathione S-transferase Mu 1;GST class-mu 1;GST HB subunit 4;GST1;Gstm1;GSTM1-1;GSTM1;GSTM1a-1a;GSTM1b-1b;GTH4;GTM1;H-B;LIVER AND FIBROBLAST GST1;MU;MU-1

Active Protein: N/A

Activity: A DNA sequence encoding the Mouse Gstm1 (P10649-1) (Pro2-Lys218) was expressed with a polyhistidine tag at the N-terminus.

Protein Construction: A DNA sequence encoding the Mouse Gstm1 (P10649-1) (Pro2-Lys218) was expressed with a polyhistidine tag at the N-terminus.

Fusion Tag: N-His

Species: Mouse

Expressed Host: E.coli

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: Please contact us for more information.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 25.7 kDa

Formulation: Lyophilized from sterile PBS, pH 7.4

Reconstitution: Please refer to the printed manual for detailed information.

Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.

Research Area: N/A