Description
Recombinant Mouse Galectin-3/Lgals3 protein (His Tag) | PKSM500006 | Gentaur US, UK & Europe Disrtribition
Synonyms: 35 kDa lectin, Carbohydrate binding protein 35, CBP35, GAL3, GALBP, GALIG, GBP, Gal-3, IgE binding protein, LGALS2, Macrophage galactose-specific lectin, Lectin L-29, Mac-2 antigen
Active Protein: Active protein
Activity: A DNA sequence encoding the Mouse Galectin-3/Lgals3 protein (P16110) (2A-264I) was expressed with a polyhistidine tag at the N-terminus.
Protein Construction: A DNA sequence encoding the Mouse Galectin-3/Lgals3 protein (P16110) (2A-264I) was expressed with a polyhistidine tag at the N-terminus.
Fusion Tag: N/C-His
Species: Mouse
Expressed Host: E.coli
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 90 % as determined by reducing SDS-PAGE.
Endotoxin: Please contact us for more information.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 27.4kDa
Formulation: Lyophilized from sterile PBS, pH 7.4
Reconstitution: Please refer to the printed manual for detailed information.
Background: Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes.
Research Area: N/A
