Recombinant Mouse FAP protein (His Tag) | PKSM500005

Recombinant Mouse FAP protein (His Tag) | PKSM500005 | Gentaur US, UK & Europe Disrtribition

Synonyms: 170 kDa melanoma membrane bound gelatinase, 170 kDa melanoma membrane-bound gelatinase, DPPIV, FAP, FAPA, Fibroblast activation protein alpha, Integral membrane serine protease, SEPR, Seprase, FAPalpha, SIMP

Active Protein: Active protein

Activity: A DNA sequence encoding the Mouse FAP protein (P97321) (26L-349G) was expressed with a polyhistidine tag at the N-terminus.

Protein Construction: A DNA sequence encoding the Mouse FAP protein (P97321) (26L-349G) was expressed with a polyhistidine tag at the N-terminus.

Fusion Tag: N/C-His

Species: Mouse

Expressed Host: E.coli

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 90 % as determined by reducing SDS-PAGE.

Endotoxin: Please contact us for more information.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 38kDa

Formulation: Lyophilized from sterile PBS, pH 7.4

Reconstitution: Please refer to the printed manual for detailed information.

Background: Cell surface glycoprotein serine protease that participates in extracellular matrix degradation and involved in many cellular processes including tissue remodeling, fibrosis, wound healing, inflammation and tumor growth. Both plasma membrane and soluble forms exhibit post-proline cleaving endopeptidase activity, with a marked preference for Ala/Ser-Gly-Pro-Ser/Asn/Ala consensus sequences, on substrate such as alpha-2-antiplasmin SERPINF2 and SPRY2. Degrade also gelatin, heat-denatured type I collagen, but not native collagen type I and IV, vibronectin, tenascin, laminin, fibronectin, fibrin or casein. Have also dipeptidyl peptidase activity, exhibiting the ability to hydrolyze the prolyl bond two residues from the N-terminus of synthetic dipeptide substrates provided that the penultimate residue is proline, with a preference for Ala-Pro, Ile-Pro, Gly-Pro, Arg-Pro and Pro-Pro. Natural neuropeptide hormones for dipeptidyl peptidase are the neuropeptide Y (NPY), peptide YY (PYY), substance P (TAC1) and brain natriuretic peptide 32 (NPPB).

Research Area: N/A