Recombinant Mouse EphA3 Protein (aa 569-984, His & GST Tag)(Active) | PKSM040288

Recombinant Mouse EphA3 Protein (aa 569-984, His & GST Tag)(Active) | PKSM040288 | Gentaur US, UK & Europe Disrtribition

Synonyms: AW492086;Cek4;End3;ETK1;Hek;Hek4;Mek4;Tyro4

Active Protein: N/A

Activity: A DNA sequence encoding the mouse EPHA3 (EDK98238.1) (Gly569-Val984) was expressed with the N-terminal polyhistidine-tagged GST tag at the N-terminus.

Protein Construction: A DNA sequence encoding the mouse EPHA3 (EDK98238.1) (Gly569-Val984) was expressed with the N-terminal polyhistidine-tagged GST tag at the N-terminus.

Fusion Tag: N-His-GST

Species: Mouse

Expressed Host: Baculovirus-Insect Cells

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.

Purity: > 90 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Molecular Mass: 74.3 kDa

Formulation: Supplied as sterile 20mM Tris, 500mM NaCl, 10% glycerol, pH 8.0

Reconstitution: Not Applicable

Background: EPHA3 gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 gene encodes a protein that binds ephrin-A ligands. EPHA3 is involved in the retinotectal mapping of neurons. It may also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development.Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Research Area: N/A