Recombinant Mouse Cyclophilin A Protein (His Tag) | PKSM040752

Recombinant Mouse Cyclophilin A Protein (His Tag) | PKSM040752 | Gentaur US, UK & Europe Disrtribition

Synonyms: 2700098C05 Protein, Mouse;Cphn Protein, Mouse;CyP-18 Protein, Mouse;CypA Protein, Mouse

Active Protein: N/A

Activity: A DNA sequence encoding the mouse PPIA (NP_032933.1) (Met 1-Leu 164) was expressed, with a polyhistide tag at the C-terminus.

Protein Construction: A DNA sequence encoding the mouse PPIA (NP_032933.1) (Met 1-Leu 164) was expressed, with a polyhistide tag at the C-terminus.

Fusion Tag: C-His

Species: Mouse

Expressed Host: E.coli

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 97 % as determined by reducing SDS-PAGE.

Endotoxin: Please contact us for more information.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 18.8 kDa

Formulation: Lyophilized from sterile PBS, pH 7.4, 10% glycerol

Reconstitution: Please refer to the printed manual for detailed information.

Background: Peptidyl-prolyl cis-trans isomerase A, also known as PPIase A, Rotamase A, Cyclophilin A, Cyclosporin A-binding protein, PPIA and CYPA, is a cytoplasm protein which belongs to the cyclophilin-type PPIase family and PPIase A subfamily. Cyclophilins (CyPs) are a family of proteins found in organisms ranging from prokaryotes to humans. These molecules exhibit peptidyl-prolyl isomerase activity, suggesting that they influence the conformation of proteins in cells. PPIA / Cyclophilin A accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIA / Cyclophilin A is secreted by vascular smooth muscle cells in response to inflammatory stimuli, and could thus contribute to atherosclerosis. It is not essential for mammalian cell viability. PPIA / Cyclophilin A can interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.

Research Area: N/A