Recombinant Mouse CD39/ENTPD1 Protein (His Tag) | PKSM041341

Recombinant Mouse CD39/ENTPD1 Protein (His Tag) | PKSM041341 | Gentaur US, UK & Europe Disrtribition

Synonyms: Ectonucleoside triphosphate diphosphohydrolase 1; NTPDase 1; NTPDase 1; Ecto-ATP diphosphohydrolase 1; Ecto-ATPDase 1; Ecto-ATPase 1; Ecto-apyrase; Lymphoid cell activation antigen; CD39

Active Protein: N/A

Activity: Recombinant Mouse ENTPD1 is produced by our Mammalian expression system and the target gene encoding Thr38-Ile478 is expressed with a 6His tag at the C-terminus.

Protein Construction: Recombinant Mouse ENTPD1 is produced by our Mammalian expression system and the target gene encoding Thr38-Ile478 is expressed with a 6His tag at the C-terminus.

Fusion Tag: C-His

Species: Mouse

Expressed Host: Human Cells

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per μg as determined by the LAL method.

Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Molecular Mass: 50.5 kDa

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris, 500mM NaCl, 10%Glycerol, pH7.4.

Reconstitution: Not Applicable

Background: Ectonucleoside triphosphate diphosphohydrolase-1(NTPDase-1)is an integral membrane protein with an extracellular active site. Recombinant mouse NTPDase-1wasexpressed as a protein lacking its N- andC-terminaltransmembrane domains, resulting in the secretion of the soluble ectodomain. NTPDase-1was originally describedas CD39, a B lymphocyte cell surface marker. but it is also present on the surface of natural killer cells, T cells, and some endothelial cells. NTPDase1hydrolyzes the β-andγ phosphate residues of nucleotides, preferring ATP as the substrate. Through its hydrolysis of extracellular nucleotides, NTPDase-1plays arole in the regulation of purinergic signaling. NTPDase-1is involved in the processes of thromboregulation and vascular inflammation. The administration ofsoluble NTPDase-1may have therapeutic applications for the treatment of some vascular and transplantation-associateddiseases.

Research Area: N/A