Recombinant Mouse APRIL/TNFSF13 Protein (Fc Tag) | PKSM041367

Recombinant Mouse APRIL/TNFSF13 Protein (Fc Tag) | PKSM041367 | Gentaur US, UK & Europe Disrtribition

Synonyms: A proliferation-inducing ligand;TNFSF13;TALL-2;TRDL-1;CD256

Active Protein: N/A

Activity: Recombinant Mouse TNFSF13 is produced by our Mammalian expression system and the target gene encoding Ala96-Leu240 is expressed with a Fc tag at the Nterminus.

Protein Construction: Recombinant Mouse TNFSF13 is produced by our Mammalian expression system and the target gene encoding Ala96-Leu240 is expressed with a Fc tag at the Nterminus.

Fusion Tag: N-Fc

Species: Mouse

Expressed Host: Human Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per μg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 42.7 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Reconstitution: Please refer to the printed manual for detailed information.

Background: Tumor necrosis factor ligand superfamily member 13 belongs to the tumor necrosis factor family. It is also known as APRIL, TALL2, TRDL1, and CD256. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. TNFSF13 is a Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA and plays a role in the regulation of tumor cell growth. It expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages. Its expression by CD4+ T cells inhibits the production of Th2 cytokines and allergic inflammation.

Research Area: N/A