Recombinant Lamin A/C Monoclonal Antibody | E-AB-81577

Recombinant Lamin A/C Monoclonal Antibody | E-AB-81577 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Application: WB, IHC-P

Research Area: Cancer, Signal Transduction, Tags and Cell Markers

Background: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants.

Lead Time: 7~10 days

Concentration: 300 μg/mL

Storage: Store at -20℃. Avoid freeze / thaw cycles.

Immunogen: N/A

Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification: Affinity Purified

Dilution: WB 1:1000-1:2000 IHC 1:50-1:100

Conjugation: Unconjugated

Calculated Molecular Weight: 74 kDa

Observed Molecular Weight: 74/63 kDa

Clonality: Rabbit Monoclonal