Recombinant Human UBE2T Protein (His Tag) | PKSH030839

Recombinant Human UBE2T Protein (His Tag) | PKSH030839 | Gentaur US, UK & Europe Disrtribition

Synonyms: Ubiquitin-Conjugating Enzyme E2 T; Cell Proliferation-Inducing Gene 50 Protein; Ubiquitin Carrier Protein T; Ubiquitin-Protein Ligase T; UBE2T

Active Protein: N/A

Activity: A DNA sequence encoding the human UBE2T (Q9NPD8) (Met1-Val197) was fused with a polyhistidine tag at the C-terminus.

Protein Construction: A DNA sequence encoding the human UBE2T (Q9NPD8) (Met1-Val197) was fused with a polyhistidine tag at the C-terminus.

Fusion Tag: C-His

Species: Human

Expressed Host: E.coli

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 90 % as determined by reducing SDS-PAGE.

Endotoxin: Please contact us for more information.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 23.9 kDa

Formulation: Lyophilized from sterile PBS, 30 % glycerol, 0.1 % Tween 20, 0.4 mM Chaps, pH 7.5

Reconstitution: Please refer to the printed manual for detailed information.

Background: Ube2T is the E2 ubiquitin-conjugating enzyme of the Fanconi anemia DNA repair pathway and it is overexpressed in several cancers; representing an attractive target for the development of inhibitors. Notably; UBE2T locates at 1q32.1; and the gain of 1q is frequently observed in a variety of cancers. For instance; UBE2T serves an important role in the growth of bladder cancer cells; and may be considered as a potential biomarker and therapeutic target for bladder cancer.

Research Area: Cell biology, epigenetics and nuclear signal