Description
Recombinant Human UBE2B/HR6B Protein | PKSH033179 | Gentaur US, UK & Europe Disrtribition
Synonyms: Ubiquitin-Conjugating Enzyme E2 B; RAD6 Homolog B; HR6B; hHR6B; Ubiquitin Carrier Protein B; Ubiquitin-Conjugating Enzyme E2-17 kDa; Ubiquitin-Protein Ligase B; UBE2B; RAD6B
Active Protein: N/A
Activity: Recombinant Human Ubiquitin-Conjugating Enzyme E2 B is produced by our E.coli expression system and the target gene encoding Met1-Ser152 is expressed.
Protein Construction: Recombinant Human Ubiquitin-Conjugating Enzyme E2 B is produced by our E.coli expression system and the target gene encoding Met1-Ser152 is expressed.
Fusion Tag:
Species: Human
Expressed Host: E.coli
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 17.5 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 10mM HEPES, pH 7.5.
Reconstitution: Not Applicable
Background: Ubiquitin-Conjugating Enzyme E2 B (UBE2B) belongs to the ubiquitin-conjugating enzyme family. UBE2B can catalyze the covalent attachment of ubiquitin to other proteins; and is essential for the multi-ubiquitination and degradation of N-end rule substrates. UBE2B is indispensability for postreplication repair of UV-damaged DNA and may be involved in neurite outgrowth.Additionally; UBE2B may have a role in sepsis-induced muscle protein proteolysis and cancer-induced cachexia.
Research Area: Cell biology, Cancer, epigenetics and nuclear signal, metabolism
