Recombinant Human TSTA3/SDR4E1 Protein (His Tag) | PKSH032483

Recombinant Human TSTA3/SDR4E1 Protein (His Tag) | PKSH032483 | Gentaur US, UK & Europe Disrtribition

Synonyms: GDP-L-Fucose Synthase; GDP-4-Keto-6-Deoxy-D-Mannose-3;5-Epimerase-4-Reductase; Protein FX; Red Cell NADP(H)-Binding Protein; Short-Chain Dehydrogenase/Reductase Family 4E Member 1; TSTA3; SDR4E1

Active Protein: N/A

Activity: Recombinant Human GDP-L-Fucose Synthase is produced by our E.coli expression system and the target gene encoding Met1-Lys321 is expressed with a 6His tag at the C-terminus.

Protein Construction: Recombinant Human GDP-L-Fucose Synthase is produced by our E.coli expression system and the target gene encoding Met1-Lys321 is expressed with a 6His tag at the C-terminus.

Fusion Tag: C-6His

Species: Human

Expressed Host: E.coli

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Molecular Mass: 37.0 kDa

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, pH 8.0.

Reconstitution: Not Applicable

Background: GDP-L-Fucose Synthase is a NADP(H)-binding protein. It catalyzes the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-dexoymannose to GDP-L-fucose. GDP-L-Fucose is the substrate of several fucosyltransferase, involving the expression of mamy glycoconjugates, including blood group ABH antigens and development adhesion antigens. Mutations in the TSTA3 gene may cause leukocyte adhesion deficiency type II.

Research Area: Signal Transduction, metabolism,