Description
Recombinant Human TRIM/TRAT1 Protein (His Tag) | PKSH033097 | Gentaur US, UK & Europe Disrtribition
Synonyms: T-Cell Receptor-Associated Transmembrane Adapter 1; T-Cell Receptor-Interacting Molecule; TRIM; pp29/30; TRAT1; TCRIM; HSPC062
Active Protein: N/A
Activity: Recombinant Human T Cell Receptor Interacting Molecule is produced by our E.coli expression system and the target gene encoding Asn29-Asn186 is expressed with a 6His tag at the C-terminus.
Protein Construction: Recombinant Human T Cell Receptor Interacting Molecule is produced by our E.coli expression system and the target gene encoding Asn29-Asn186 is expressed with a 6His tag at the C-terminus.
Fusion Tag: C-6His
Species: Human
Expressed Host: E.coli
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 19.4 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 10% Glycerol, pH7.4.
Reconstitution: Not Applicable
Background: T-Cell Receptor-Associated Transmembrane Adapter 1 (TRAT1) is a single-pass type III membrane protein. TRAT1 exists as a disulfide-linked homodimer and is strongly expressed in the thymus, and to a lesser extent in the spleen, lymph node, and peripheral blood lymphocytes. TRAT1 is phosphorylated on tyrosines by LCK or FYN upon TCR activation. Its function is to stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.
Research Area: Signal Transduction, immunology,
