Recombinant Human TNFSF4/OX40L Protein (mFc Tag) | PKSH033572

Recombinant Human TNFSF4/OX40L Protein (mFc Tag) | PKSH033572 | Gentaur US, UK & Europe Disrtribition

Synonyms: Tumor necrosis factor ligand superfamily member 4;Glycoprotein Gp34;OX40 ligand;OX40L;TAX transcriptionally-activated glycoprotein 1;TNFSF4;CD252;TXGP1;CD134L;CD252;GP34;OX-40;TXGP1

Active Protein: N/A

Activity: Recombinant Human OX40L is produced by our Mammalian expression system and the target geneencoding Gln51-Leu183 is expressed with a mFc tag at the C-terminus.

Protein Construction: Recombinant Human OX40L is produced by our Mammalian expression system and the target geneencoding Gln51-Leu183 is expressed with a mFc tag at the C-terminus.

Fusion Tag: C-mFc

Species: Human

Expressed Host: Human Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per μg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 42.2 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Reconstitution: Please refer to the printed manual for detailed information.

Background: Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed on the surface of activated B cells;T cells;dendritic cells and endothelial cells. OX40L binds to OX40(CD134);a member of the TNF receptor superfamily that is expressed predominantly on activated CD4+ T cells. OX40-OX40L co-stimulates signal to promote the survival and proliferation of activated CD4+ T cells and prolong the immune response. It involved in T-cell proliferation and cytokine production. Additional;it has been found association with systemic lupus erythematosus;no association with occurrence of atherosclerosis.

Research Area: immunology, Stem cells