Recombinant Human THAP1 protein(His tag) | PKSH500094

Recombinant Human THAP1 protein(His tag) | PKSH500094 | Gentaur US, UK & Europe Disrtribition

Synonyms: THAP domain-containing protein 1

Active Protein: N/A

Activity: A DNA sequence encoding theHuman THAP1 protein (Q9NVV9) (Met1-Phe81) was expressed with a N-His.

Protein Construction: A DNA sequence encoding theHuman THAP1 protein (Q9NVV9) (Met1-Phe81) was expressed with a N-His.

Fusion Tag: His

Species: Human

Expressed Host: E.coli

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 80 % as determined by reducing SDS-PAGE.

Endotoxin: Please contact us for more information.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 9.5 kDa

Formulation: Lyophilized from sterile PBS, pH 7.5, 5% trehalose, 5% mannitol, 0.01% tween-80.

Reconstitution: Please refer to the printed manual for detailed information.

Background: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. May also have pro-apoptotic activity by potentiating both serum-withdrawal and TNF-induced apoptosis.

Research Area: N/A