Recombinant Human Tetherin/BST2 Protein (Fc Tag) | PKSH030644

Recombinant Human Tetherin/BST2 Protein (Fc Tag) | PKSH030644 | Gentaur US, UK & Europe Disrtribition

Synonyms: Bone Marrow Stromal Antigen 2; BST-2; HM1.24 Antigen; Tetherin; CD317; BST2

Active Protein: N/A

Activity: A DNA sequence encoding the human BST2 (Q10589) (Asn49-Ser160) was expressed;with the fused Fc region of human IgG1 at the N-terminus.

Protein Construction: A DNA sequence encoding the human BST2 (Q10589) (Asn49-Ser160) was expressed;with the fused Fc region of human IgG1 at the N-terminus.

Fusion Tag: N-Fc

Species: Human

Expressed Host: HEK293 Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 90 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg of the protein as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 41 kDa

Formulation: Lyophilized from sterile PBS, pH 7.4

Reconstitution: Please refer to the printed manual for detailed information.

Background: CLM-9; also known as TREM4; is a receptor which belongs to the TREM family. The TREM family of receptors regulates the activity of various cell types of the immune system including neutrophils; monocyte/macrophages; microglia; and dendritic cells. CLM-9 may mediate L-selectin-dependent lymphocyte rollings. It binds SELL in a calcium dependent manner. CLM-9 also binds lymphocyte which suggests that it functions in lymphocyte adhesion. The major CLM-9 transcript is expressed highly in human heart; skeletal muscle; and placenta. The mouse protein has been shown to be expressed in capillary endothelial cells. Human CLM-9 mediates the uptake of human IgA2 and mouse IgM.

Research Area: Signal Transduction, Tags & Cell Markers, Cardiovascular, epigenetics and nuclear signal, immunology, Stem cells