Recombinant Human Testin/TES Protein (His Tag) | PKSH033102

Recombinant Human Testin/TES Protein (His Tag) | PKSH033102 | Gentaur US, UK & Europe Disrtribition

Synonyms: Testin; TESS; TES

Active Protein: N/A

Activity: Recombinant Human Testin is produced by our E.coli expression system and the target gene encoding Met1-Ser421 is expressed with a 6His tag at the C-terminus.

Protein Construction: Recombinant Human Testin is produced by our E.coli expression system and the target gene encoding Met1-Ser421 is expressed with a 6His tag at the C-terminus.

Fusion Tag: C-6His

Species: Human

Expressed Host: E.coli

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 49.1 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM DTT, pH 7.2.

Reconstitution: Please refer to the printed manual for detailed information.

Background: Testin belongs to the prickle/espinas/testin family. Testin contains three LIM zinc-binding domains and one PET domain, TES as a scaffold protein that may have a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. In addition, TES can also as a tumor suppressor, inhibits tumor cell growth, regulate the cell proliferation.TES interacts with many cytoskeletal proteins, such as Zyxin, Mena, Actin, Talin and VASP. The ability of TES to associate with alpha-actin, Zyxin and paxillin is dependent on the conformational state of the molecule.

Research Area: Signal Transduction, Cancer, epigenetics and nuclear signal,