Recombinant Human TEM7/PLXDC1 Protein (His Tag) | PKSH032908

Recombinant Human TEM7/PLXDC1 Protein (His Tag) | PKSH032908 | Gentaur US, UK & Europe Disrtribition

Synonyms: Plexin Domain-Containing Protein 1; Tumor Endothelial Marker 3; Tumor Endothelial Marker 7; PLXDC1; TEM3; TEM7

Active Protein: N/A

Activity: Recombinant Human Plexin Domain-Containing Protein 1 is produced by our Mammalian expression system and the target gene encoding Leu19-Thr426 is expressed with a 6His tag at the C-terminus.

Protein Construction: Recombinant Human Plexin Domain-Containing Protein 1 is produced by our Mammalian expression system and the target gene encoding Leu19-Thr426 is expressed with a 6His tag at the C-terminus.

Fusion Tag: C-6His

Species: Human

Expressed Host: Human Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 46.5 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 5% Threhalose, pH 7.2.

Reconstitution: Please refer to the printed manual for detailed information.

Background: Plexin Domain-Containing Protein 1 (PLXDC1) is a single-pass type I membrane protein that belongs to the plexin family. Secreted PLXDC1 is localized predominantly at the tight junctions of vascular endothelial cells and to a lesser extent at the luminal surface of vascular endothelial cells. PLXDC1 is expressed in fibrovascular membrane with increased expression in individuals with proliferative diabetic retinopathy. It can detect in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. PLXDC1 interacts with NID1 and may also interact with CTTN. It plays a important role in endothelial cell capillary morphogenesis, the proliferation and maintenance of neovascular endothelial cells in the formation of fibrovascular membranes (FVMs).

Research Area: Tags & Cell Markers, Cardiovascular