Description
Recombinant Human Syndecan-1/SDC1 Protein (Fc Tag) | PKSH033514 | Gentaur US, UK & Europe Disrtribition
Synonyms: Syndecan-1; SYND1; CD138; SDC1; SDC
Active Protein: N/A
Activity: Recombinant Human Syndecan-1 is produced by our Mammalian expression system and the target gene encoding Gln18-Glu251(Leu136Gln) is expressed with a Fc tag at the C-terminus.
Protein Construction: Recombinant Human Syndecan-1 is produced by our Mammalian expression system and the target gene encoding Gln18-Glu251(Leu136Gln) is expressed with a Fc tag at the C-terminus.
Fusion Tag: C-Fc
Species: Human
Expressed Host: Human Cells
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per μg as determined by the LAL method.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 51 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 .
Reconstitution: Please refer to the printed manual for detailed information.
Background: Syndecan-1 is a single-pass type I membrane protein that belongs to the syndecan proteoglycan family. The syndecans mediate cell binding; cell signaling; and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. Human SDC1 is synthesized as a 310 amino acid precursor that contains a 22 amino acid signal sequence; and a 288 amino acid mature chain. The Syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation; cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered Syndecan-1 expression has been detected in several different tumor types.
Research Area: Signal Transduction, Neuroscience, Cancer, metabolism, Stem cells
