Recombinant Human SUSD4/Sushi domain-containing protein 4 Protein (Fc Tag) | PKSH030623

Recombinant Human SUSD4/Sushi domain-containing protein 4 Protein (Fc Tag) | PKSH030623 | Gentaur US, UK & Europe Disrtribition

Synonyms: PRO222

Active Protein: N/A

Activity: A DNA sequence encoding the human SUSD4 (Q5VX71-3) (Met1-Phe290) was fused with Fc region of mouse IgG at the C-terminus.

Protein Construction: A DNA sequence encoding the human SUSD4 (Q5VX71-3) (Met1-Phe290) was fused with Fc region of mouse IgG at the C-terminus.

Fusion Tag: C-Fc

Species: Human

Expressed Host: HEK293 Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 85 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 53.8 kDa

Formulation: Lyophilized from sterile PBS, pH 7.4

Reconstitution: Please refer to the printed manual for detailed information.

Background: SUSD4, also known as sushi domain-containing protein 4, is a hypothetical cell surface protein whose tissue distribution and function are completely unknown. SUSD4 is detectable in murine brains, eyes, spinal cords, and testis but not other tissues. In brains, SUSD4 is highly expressed in the white matter on oligodendrocytes/axons, and in eyes, it is exclusively expressed on the photoreceptor outer segments. In in vitro complement assays, SUSD4 augments the alternative but not the classical pathway of complement activation at the C3 convertase step. SUSD4 deficiency may cause autism or Fryns syndrome, both of which are genetic diseases with severe abnormal neurological development and/or functions.

Research Area: N/A