Description
Recombinant Human STK24/MST3 Protein (His Tag)(Active) | PKSH030330 | Gentaur US, UK & Europe Disrtribition
Synonyms: HEL-S-95;MST3;MST3B;RP11-111L24.5;STE20;STK3
Active Protein: Active protein
Activity: A DNA sequence encoding the human STK24 isoform A (Q9Y6E0-2) (Met 1-His 431) was expressed, with a polyhistidine tag at the N-terminus.
Protein Construction: A DNA sequence encoding the human STK24 isoform A (Q9Y6E0-2) (Met 1-His 431) was expressed, with a polyhistidine tag at the N-terminus.
Fusion Tag: N-His
Species: Human
Expressed Host: Baculovirus-Insect Cells
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 82 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 50.3 kDa
Formulation: Supplied as sterile 50mM Tris, 100mM NaCl, pH 8.0, 20% gly, 0.1mM EGTA, 0.1mM EDTA, 0.25mM DTT
Reconstitution: Not Applicable
Background: MST3 encodes a serine/threonine protein kinase that functions upstream of mitogen-activated protein kinase (MAPK) signaling. The encoded protein is cleaved into two chains by caspases; the N-terminal fragment (MST3/N) translocates to the nucleus and promotes programmed cells death. There is a pseudogene for this gene on chromosome X. Alternative splicing results in multiple transcript variants.
Research Area: N/A