Recombinant Human ST8SIA1 Protein (His Tag) | PKSH033251

Recombinant Human ST8SIA1 Protein (His Tag) | PKSH033251 | Gentaur US, UK & Europe Disrtribition

Synonyms: Alpha-N-Acetylneuraminide Alpha-2;8-Sialyltransferase; Alpha-2;8-Sialyltransferase 8A; Ganglioside GD3 Synthase; Ganglioside GT3 Synthase; Sialyltransferase 8A; SIAT8-A; Sialytransferase St8Sia I; ST8SiaI; ST8SIA1; SIAT8; SIAT8A

Active Protein: N/A

Activity: Recombinant Human alpha-N-Acetylneuraminide alpha-2, 8-Sialyltransferase is produced by our Mammalian expression system and the target gene encoding Tyr49-Ser356 is expressed with a 6His tag at the C-terminus.

Protein Construction: Recombinant Human alpha-N-Acetylneuraminide alpha-2, 8-Sialyltransferase is produced by our Mammalian expression system and the target gene encoding Tyr49-Ser356 is expressed with a 6His tag at the C-terminus.

Fusion Tag: C-6His

Species: Human

Expressed Host: Human Cells

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Molecular Mass: 36.2 kDa

Formulation: Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH8.0.

Reconstitution: Not Applicable

Background: α-N-Acetylneuraminide α-2, 8-Sialyltransferase (ST8SIA1) belongs to the glycosyltransferase 29 family. ST8SIA1 is a sialytransferase that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce GD3 and GT3. ST8SIA1 is highly expressed in melanoma cell lines, adult and fetal brain, low expressed in adult and fetal lung. ST8SIA1 may act as a type II transmembrane protein with a short N-termianl cytoplasmic domain and a single-pass transmembrane domain folowed by an enzymatic domain in the lument of the Golgi apparatus.

Research Area: Signal Transduction, Cancer, metabolism,