Recombinant Human SOD2/Mn-SOD Protein (His Tag) | PKSH033072

Recombinant Human SOD2/Mn-SOD Protein (His Tag) | PKSH033072 | Gentaur US, UK & Europe Disrtribition

Synonyms: Superoxide Dismutase [Mn] Mitochondrial; SOD2

Active Protein: N/A

Activity: Recombinant Human Superoxide Dismutase [Mn] Mitochondrial is produced by our E.coli expression system and the target gene encoding Lys25-Lys222 is expressed with a 6His tag at the N-terminus.

Protein Construction: Recombinant Human Superoxide Dismutase [Mn] Mitochondrial is produced by our E.coli expression system and the target gene encoding Lys25-Lys222 is expressed with a 6His tag at the N-terminus.

Fusion Tag: N-6His

Species: Human

Expressed Host: E.coli

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Molecular Mass: 23.7 kDa

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris, 100mM NaCl, 50% glycerol, pH 8.0.

Reconstitution: Not Applicable

Background: Superoxide Dismutase (SOD2) is a number of the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. The SOD2 protein transforms toxic superoxide and a byproduct of the mitochondrial electron transport chain into hydrogen peroxide and diatomic oxygen. Genetic variation in SOD2 is associated with microvascular complications of diabetes type 6 (MVCD6); idiopathic cardiomyopathy (IDC); sporadic motor neuron disease; and cancer. SOD2 destroys superoxide anion radicals which are usually produced within the cells and which are toxic to biological systems.

Research Area: Signal Transduction, Cell biology, Cardiovascular, Neuroscience, Cancer, metabolism,