Description
Recombinant Human SOD2/Mn-SOD Protein (His Tag, Human Cells) | PKSH033071 | Gentaur US, UK & Europe Disrtribition
Synonyms: Superoxide Dismutase [Mn] Mitochondrial; SOD2
Active Protein: N/A
Activity: Recombinant Human Superoxide Dismutase [Mn] Mitochondrial is produced by our Mammalian expression system and the target gene encoding Lys25-Lys222 is expressed with a 6His tag at the C-terminus.
Protein Construction: Recombinant Human Superoxide Dismutase [Mn] Mitochondrial is produced by our Mammalian expression system and the target gene encoding Lys25-Lys222 is expressed with a 6His tag at the C-terminus.
Fusion Tag: C-6His
Species: Human
Expressed Host: Human Cells
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 23.2 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH8.0.
Reconstitution: Not Applicable
Background: Superoxide Dismutase (SOD2) belongs to the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial matrix protein that forms a homotetramer and binds one manganese ion per subunit. SOD2 transforms toxic superoxide; a byproduct of the mitochondrial electron transport chain into hydrogen peroxide and diatomic oxygen. It is reported that oxidative stress plays an essential role in the development of breast cancer; while SOD2 is one of the primary enzymes that directly convert potential harmful oxidizing species to harmless metabolites.
Research Area: Signal Transduction, Cell biology, Cardiovascular, Neuroscience, Cancer, metabolism,
