Recombinant Human SHISA3 Protein (Fc Tag) | PKSH030300

Recombinant Human SHISA3 Protein (Fc Tag) | PKSH030300 | Gentaur US, UK & Europe Disrtribition

Synonyms: hShisa3

Active Protein: N/A

Activity: A DNA sequence encoding the human SHISA3 (AAI27691.1) (Met1-Pro98) was expressed with the Fc region of mouse IgG1 at the C-terminus.

Protein Construction: A DNA sequence encoding the human SHISA3 (AAI27691.1) (Met1-Pro98) was expressed with the Fc region of mouse IgG1 at the C-terminus.

Fusion Tag: C-Fc

Species: Human

Expressed Host: HEK293 Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 90 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 34.9 kDa

Formulation: Lyophilized from sterile PBS, pH 7.4

Reconstitution: Please refer to the printed manual for detailed information.

Background: SHISA3 encodes a single-transmembrane protein which is one of nine members of a family of transmembrane adaptors that modulate both WNT and FGF signaling by blocking the maturation and transport of their receptors to the cell surface. Members of this family contain an N-terminal cysteine-rich domain with a distinct cysteine pattern, a single transmembrane domain, and a C-terminal proline-rich, low complexity region. The encoded protein acts as a tumor suppressor by accelerating beta-catenin degradation.

Research Area: N/A