Recombinant Human SerpinA3/AACT Protein (His Tag) | PKSH033032

Recombinant Human SerpinA3/AACT Protein (His Tag) | PKSH033032 | Gentaur US, UK & Europe Disrtribition

Synonyms: Alpha-1-Antichymotrypsin; ACT; Cell Growth-Inhibiting Gene 24/25 Protein; Serpin A3; SERPINA3; AACT;GIG24;GIG25;MGC88254;SERPINA3

Active Protein: N/A

Activity: Recombinant Human Serine Protease Inhibitor-clade A3 is produced by our Mammalian expression system and the target gene encoding His24-Ala423 is expressed with a 6His tag at the C-terminus.

Protein Construction: Recombinant Human Serine Protease Inhibitor-clade A3 is produced by our Mammalian expression system and the target gene encoding His24-Ala423 is expressed with a 6His tag at the C-terminus.

Fusion Tag: C-6His

Species: Human

Expressed Host: Human Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 90 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 46.3 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM HEPES, 150mM NaCl, pH 7.5.

Reconstitution: Please refer to the printed manual for detailed information.

Background: Serpin A3 belongs to the Serpin superfamily of serine protease inhibitors. Serpin A3 has been shown to inhibit some serine proteases, such as neutrophil cathepsin G and mast cell chymase. Serpin A3 is synthesized initially in the liver and secreted in plasma. Serpin A3 has been found in the amyloid plaques from the hippocampus of Alzheimer disease brains. In addition to, Serpin A3 is associated with liver disease and Parkinson disease and chronic obstructive pulmonary disease.

Research Area: Cell biology, Cardiovascular, Neuroscience