Recombinant Human SEPHS1 Protein (His Tag) | PKSH033016

Recombinant Human SEPHS1 Protein (His Tag) | PKSH033016 | Gentaur US, UK & Europe Disrtribition

Synonyms: Selenide; water dikinase 1;Selenium donor protein 1;Selenophosphate synthase 1;SEPHS1;SELD; SPS; SPS1

Active Protein: N/A

Activity: Recombinant Human Selenophosphate synthase is produced by our Mammalian expression system and the target gene encoding Met1-Ser392 is expressed with a 6His tag at the C-terminus.

Protein Construction: Recombinant Human Selenophosphate synthase is produced by our Mammalian expression system and the target gene encoding Met1-Ser392 is expressed with a 6His tag at the C-terminus.

Fusion Tag: C-6His

Species: Human

Expressed Host: Human Cells

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Molecular Mass: 43.9 kDa

Formulation: Supplied as a 0.2 μm filtered solution of 25mM Tris.HCl, pH7.3, 100mM glycine, 10% glycerol.

Reconstitution: Not Applicable

Background: Selenophosphate synthetase 1 (SEPHS1) belongs to the selenophosphate synthase 1 family, Class II subfamily. It has four different isoforms by alternative splicing. Isoform 1 and isoform 2 are gradually expressed during the cell cycle until G2/M phase and then decreased, which Isoform 3 is gradually expressed during the cell cycle until S phase and then decreased. SEPHS1 can be activated by phosphate ions and by potassium ions. It can synthesize synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons.

Research Area: Cell biology