Description
Recombinant Human SENP2 Protein (His Tag, SUMO Tag) | PKSH033026 | Gentaur US, UK & Europe Disrtribition
Synonyms: Sentrin-specific protease 2; Axam2; SMT3-specific isopeptidase 2; Sentrin/SUMO-specific protease SENP2; KIAA1331; SENP2.
Active Protein: N/A
Activity: Recombinant Human Sentrin-specific protease 2 is produced by our E.coli expression system and the target gene encoding Asp363-Leu589 is expressed.
Protein Construction: Recombinant Human Sentrin-specific protease 2 is produced by our E.coli expression system and the target gene encoding Asp363-Leu589 is expressed.
Fusion Tag: N-6His
Species: Human
Expressed Host: E.coli
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 26.8 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 50mM HEPES, 5% Glycerol, pH 7.4.
Reconstitution: Not Applicable
Background: SENP2 is an enzyme that belongs to the peptidase C48 family. SENP2 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SUMO1 is a small ubiquitin-like protein that can be covalently conjugated to other proteins. It has been implicated as a down-regulator of CTNNB1 levels and may therefore be a modulator of the Wnt pathway.
Research Area: Cell biology, epigenetics and nuclear signal
