Recombinant Human Secretogranin 3/SCG3 Protein (His Tag) | PKSH030513

Recombinant Human Secretogranin 3/SCG3 Protein (His Tag) | PKSH030513 | Gentaur US, UK & Europe Disrtribition

Synonyms: Secretogranin-3;Secretogranin III;SgIII;

Active Protein: N/A

Activity: A DNA sequence encoding the human SCG3 (AAH14539.1) (Met1-Leu468) was expressed with a C-terminal polyhistidine tag.

Protein Construction: A DNA sequence encoding the human SCG3 (AAH14539.1) (Met1-Leu468) was expressed with a C-terminal polyhistidine tag.

Fusion Tag: C-His

Species: Human

Expressed Host: HEK293 Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg of the protein as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 52.4 kDa

Formulation: Lyophilized from sterile PBS, pH 7.4

Reconstitution: Please refer to the printed manual for detailed information.

Background: SCG3, also known as secretogranin 3, is a member of the chromogranin/secretogranin family. Members of this family may serve as precursors for biologically active peptides. SCG3 is transported to secretory granules (SGs) in neuroendocrine cells. SCG3 binds strongly to chromogranin A (CgA) in an intragranular milieu and targets CgA to SGs in pituitary and pancreatic endocrine cells. With a sucrose density gradient of rat insulinoma-derived INS-1 cell homogenates, SgIII is localized to the SG fraction and is fractionated to the SG membrane (SGM) despite lacking the transmembrane region.

Research Area: N/A