Description
Recombinant Human SAA4 Protein (GST Tag) | PKSH031155 | Gentaur US, UK & Europe Disrtribition
Synonyms: Serum Amyloid A-4 Protein; Constitutively Expressed Serum Amyloid A Protein; C-SAA; SAA4; CSAA
Active Protein: N/A
Activity: A DNA sequence encoding the mature form of human SAA4 (P35542) (Glu19-Tyr130) was fused with the GST tag at the N-terminus.
Protein Construction: A DNA sequence encoding the mature form of human SAA4 (P35542) (Glu19-Tyr130) was fused with the GST tag at the N-terminus.
Fusion Tag: N-GST
Species: Human
Expressed Host: E.coli
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 93 % as determined by reducing SDS-PAGE.
Endotoxin: Please contact us for more information.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 39.8kDa
Formulation: Lyophilized from sterile PBS, 0.5% Triton X-100, pH 7.4
Reconstitution: Please refer to the printed manual for detailed information.
Background: SAA4 is a member of the SAA family.SAA proteins are family of apolipoproteins of high density lipoprotein (HDL). They can be separated into two distinct groups. First group (SAA1; SAA2; and SAA3) consists of acute phase reactant whose expression level increase in the blood in a response to trauma; infection; inflammation; and neoplasia. These acute phase SAAs associates with HDL during inflammation and remodel the HDL particle by displacing Apo-A1. The second distinct group consists of SAA4 and SAA5 which exist as the minor apolipoproteins on HDL; but this group of SAA constitutes more than 90% of all the SAA during homeostasis; and it is thought to play a role in the normal functioning of the HDL particle. SAA4 is a constitutively expressed protein which expressed only in humans and mice.It is connected almost completely with lipoproteins of the high density range. The physiological function of SAA4 is unknown; and its serum concentration has no association with those of other major apolipoproteins.
Research Area: Cardiovascular, Cancer, metabolism
