Description
Recombinant Human S100A6 Protein (Baculovirus, His Tag) | PKSH031347 | Gentaur US, UK & Europe Disrtribition
Synonyms: S100A6;Protein S100-A6;Calcyclin;Growth factor-inducible protein 2A9;MLN 4;Prolactin receptor-associated protein;PRA;S100 calcium-binding protein A6;CACY;2A9;5B10;CABP;PRA
Active Protein: N/A
Activity: A DNA sequence encoding the human S100A6 (NP_055439.1) (Met 1-Gly 90) was expressed; with a C-terminal polyhistidine tag.
Protein Construction: A DNA sequence encoding the human S100A6 (NP_055439.1) (Met 1-Gly 90) was expressed; with a C-terminal polyhistidine tag.
Fusion Tag: C-His
Species: Human
Expressed Host: Baculovirus-Insect Cells
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 96 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 12 kDa
Formulation: Lyophilized from sterile 50mM Tris, 100mM NaCl, 0.5mM PMSF, 1mM TCEP, pH 8.0
Reconstitution: Please refer to the printed manual for detailed information.
Background: S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins; and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer; and is normally present in cells derived from the neural crest; chondrocytes; macrophages; dendritic cells; etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation; transcription factors; the dynamics of cytoskeleton constituents; enzyme activities; cell growth and differentiation; and the inflammatory response. S100A6 (S100 calcium binding protein A6) is a member of the S100 family of proteins; and functions in prolactin secretion; and exocytosis. Chromosomal rearrangements and altered expression of S100A6 have been implicated in melanoma.
Research Area: Cell biology, epigenetics and nuclear signal
