Recombinant Human RCN2 (C-6His) | PKSH034035

Recombinant Human RCN2 (C-6His) | PKSH034035 | Gentaur US, UK & Europe Disrtribition

Synonyms: Reticulocalbin-2; RCN2; E6BP; ERC55

Active Protein: N/A

Activity: Recombinant Human Reticulocalbin-2 is produced by our Mammalian expression system and the target gene encoding Gly23-Leu317 is expressed with a 6His tag at the C-terminus.

Protein Construction: Recombinant Human Reticulocalbin-2 is produced by our Mammalian expression system and the target gene encoding Gly23-Leu317 is expressed with a 6His tag at the C-terminus.

Fusion Tag: C-6His

Species: Human

Expressed Host: Human Cells

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Molecular Mass: 35.6 kDa

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 10% Glycerol, 1mM DTT, pH 8.0.

Reconstitution: Not Applicable

Background: Reticulocalbin-2 (RCN2, also named as ERC-55), is a 55-kDa Ca2+-binding protein containing six EF-hands, which was identified to be localized in endoplasmic reticulum. RCN2 is belonging to Reticulocalbin (RCN) family, the family members could play oncogenic roles in human malignancies and facilitate tumor cell proliferation and metastasis. Recently, studies on RCN2 functions mainly focused on its role in differentiation and endocrine regulation in mouse. Another study has suggested that RCN2 could be a potential tumor-associated antigen for mammary cancer immunological prevention. Up to now, the experimental evidence uncovering the role of RCN2 in cancer is very limited.

Research Area: N/A