Recombinant Human Purine nucleoside phosphorylase/PNP Protein (His Tag) | PKSH030904

Recombinant Human Purine nucleoside phosphorylase/PNP Protein (His Tag) | PKSH030904 | Gentaur US, UK & Europe Disrtribition

Synonyms: NP;PRO1837;PUNP

Active Protein: N/A

Activity: A DNA sequence encoding the human PNP (P00491) (Met 1-Ser 289) was fused with a polyhistide tag at the C-terminus.

Protein Construction: A DNA sequence encoding the human PNP (P00491) (Met 1-Ser 289) was fused with a polyhistide tag at the C-terminus.

Fusion Tag: C-His

Species: Human

Expressed Host: E.coli

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 97 % as determined by reducing SDS-PAGE.

Endotoxin: Please contact us for more information.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 33.5 kDa

Formulation: Lyophilized from sterile PBS, 25% glycerol, pH 7.5

Reconstitution: Please refer to the printed manual for detailed information.

Background: RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that forms after a brain injury. This protein may also function as a tumor suppressor in some cancers.

Research Area: Neuroscience