Description
Recombinant Human PTH2/PTRH2 Protein (His Tag) | PKSH030587 | Gentaur US, UK & Europe Disrtribition
Synonyms: BIT1;CFAP37;CGI-147;IMNEPD;PTH;PTH 2;PTH2;PTRH2
Active Protein: N/A
Activity: A DNA sequence encoding the human PTRH2 (Q9Y3E5) (Gly63-Tyr179) was expressed with a polyhistidine tag at the N-terminus.
Protein Construction: A DNA sequence encoding the human PTRH2 (Q9Y3E5) (Gly63-Tyr179) was expressed with a polyhistidine tag at the N-terminus.
Fusion Tag: N-His
Species: Human
Expressed Host: E.coli
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: Please contact us for more information.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 14.5 kDa
Formulation: Lyophilized from sterile 20mM Tris, 10% glycerol, pH 8.0
Reconstitution: Please refer to the printed manual for detailed information.
Background: PTH2, also known as PTRH2, is a mitochondrial protein which belongs to the PTH2 family. PTH 2 is released during apoptosis from the mitochondria to the cytoplasm. The natural substrate for PTH 2 may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. When in the cytoplasm, PTRH2 regulates the function of 2 transcriptional regulators, TLE5 and TLE1, thus promoting caspase-independent cell death.
Research Area: Cell biology, Cancer, epigenetics and nuclear signal, metabolism
