Recombinant Human Protocadherin-1/PCDH1 Protein (His Tag) | PKSH032977

Recombinant Human Protocadherin-1/PCDH1 Protein (His Tag) | PKSH032977 | Gentaur US, UK & Europe Disrtribition

Synonyms: Protocadherin-1; Cadherin-Like Protein 1; Protocadherin-42; PC42; PCDH1

Active Protein: N/A

Activity: Recombinant Human Protocadherin-1 is produced by our Mammalian expression system and the target gene encoding Thr58-Asn852 is expressed with a 6His tag at the C-terminus.

Protein Construction: Recombinant Human Protocadherin-1 is produced by our Mammalian expression system and the target gene encoding Thr58-Asn852 is expressed with a 6His tag at the C-terminus.

Fusion Tag: C-6His

Species: Human

Expressed Host: Human Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 87.3 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Reconstitution: Please refer to the printed manual for detailed information.

Background: Protocadherin-1, also known as Cadherin-like protein 1, Protocadherin-42 and PCDH1, belongs to the protocadherin subfamily within the cadherin superfamily. PCDH1 contains seven cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. PCDH1 can be detected as early as embryonic day 9.5. In early embryogenesis, expression is especially prominent in blood vessels. The tight spatial and temporal regulation of Pcdh1 expression suggests that this protocadherin plays multiple roles not only during development but also in mature tissues and organs. In addition, protocadherin-1 is involved in cell-cell interaction processes and in neural cell adhesion.

Research Area: Signal Transduction, Neuroscience,