Recombinant Human PPIase/PPIL1 Protein (aa 1-166, His Tag) | PKSH033304

Recombinant Human PPIase/PPIL1 Protein (aa 1-166, His Tag) | PKSH033304 | Gentaur US, UK & Europe Disrtribition

Synonyms: Peptidyl-Prolyl Cis-Trans Isomerase-Like 1; PPIase; Rotamase PPIL1; PPIL1; CYPL1

Active Protein: N/A

Activity: Recombinant Human Peptidyl-Prolyl Cis-Trans Isomerase-Like 1 is produced by our E.coli expression system and the target gene encoding Met1-Gly166 is expressed with a 6His tag at the N-terminus.

Protein Construction: Recombinant Human Peptidyl-Prolyl Cis-Trans Isomerase-Like 1 is produced by our E.coli expression system and the target gene encoding Met1-Gly166 is expressed with a 6His tag at the N-terminus.

Fusion Tag: N-6His

Species: Human

Expressed Host: E.coli

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.

Purity: > 90 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Molecular Mass: 20.4 kDa

Formulation: Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, pH 8.0.

Reconstitution: Not Applicable

Background: Peptidyl-Prolyl Cis-Trans Isomerase-Like 1 (PPIase) belongs to the cyclophilin-type PPIase family. PPIases can accelerate the folding of proteins and catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIase is a ubiquitous protein and has highly expression in heart ;skeletal and muscle. PPIase contains a PPIase cyclophilin-type domain and four Cyclosporin A binding regions. PPIase might play an important role in proliferation of cancer cells through modulation of phosphorylation of stathmin. It is suggested that PPIase can act as as a novel molecular target for colon-cancer therapy.

Research Area: Signal Transduction, epigenetics and nuclear signal, immunology,