Description
Recombinant Human PIGR Protein (Fc Tag) | PKSH032914 | Gentaur US, UK & Europe Disrtribition
Synonyms: Polymeric Immunoglobulin Receptor; PIgR; Poly-Ig Receptor; Hepatocellular Carcinoma-Associated Protein TB6; PIGR
Active Protein: N/A
Activity: Recombinant Human Polymeric immunoglobulin receptor is produced by our Mammalian expression system and the target gene encoding Lys19-Arg638 is expressed with a Fc tag at the C-terminus.
Protein Construction: Recombinant Human Polymeric immunoglobulin receptor is produced by our Mammalian expression system and the target gene encoding Lys19-Arg638 is expressed with a Fc tag at the C-terminus.
Fusion Tag: C-Fc
Species: Human
Expressed Host: Human Cells
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 95.0 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, pH 8.0.
Reconstitution: Please refer to the printed manual for detailed information.
Background: PIGR binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.
Research Area: immunology
