Description
Recombinant Human PGD Protein (E.coli, His Tag) | PKSH031635 | Gentaur US, UK & Europe Disrtribition
Synonyms: 6-phosphogluconate dehydrogenase; Decarboxylating;PGD;PGDH;6PGD
Active Protein: N/A
Activity: A DNA sequence encoding the human PGD (P52209) (Met 1-Ala 483) was expressed; with a polyhistide tag at the N-terminus.
Protein Construction: A DNA sequence encoding the human PGD (P52209) (Met 1-Ala 483) was expressed; with a polyhistide tag at the N-terminus.
Fusion Tag: N-His
Species: Human
Expressed Host: E.coli
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 88 % as determined by reducing SDS-PAGE.
Endotoxin: Please contact us for more information.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 54.6 kDa
Formulation: Lyophilized from sterile PBS, pH 8.0
Reconstitution: Please refer to the printed manual for detailed information.
Background: 6-phosphogluconate dehydrogenase(PGD) is a cytoplasm-located protein; and belongs to the 6-phosphogluconate dehydrogenase family. 6PGD is the second dehydrogenase in the pentose phosphate shunt. It catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO2; with concomitant reduction of NADP to NADPH. Mutations within the gene coding this enzyme result in 6-phosphogluconate dehydrogenase deficiency; an autosomal hereditary disease effecting the red blood cells.
Research Area: Signal Transduction, metabolism,
