Recombinant Human Otolin-1 (C-6His) | PKSH033958

Recombinant Human Otolin-1 (C-6His) | PKSH033958 | Gentaur US, UK & Europe Disrtribition

Synonyms: OTOL1; otolin 1; Otolin-1; C1qTNF15

Active Protein: N/A

Activity: Recombinant Human Otolin-1 is produced by our Mammalian expression system and the target gene encoding Lys24-Pro477 is expressed with a 6His tag at the C-terminus.

Protein Construction: Recombinant Human Otolin-1 is produced by our Mammalian expression system and the target gene encoding Lys24-Pro477 is expressed with a 6His tag at the C-terminus.

Fusion Tag: C-6His

Species: Human

Expressed Host: Human Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 47.7 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, 5% Trehalose, pH 7.4.

Reconstitution: Please refer to the printed manual for detailed information.

Background: Otolin (OTOL1), also known as C1qTNF15, is an approximately 65 kDa protein found in the otoconial membrane lining the cochlea and vestibular labyrinth of the inner ear. Collagen-like protein specifically expressed in the inner ear, which provides an organic scaffold for otoconia, a calcium carbonate structure in the saccule and utricle of the ear. It associates into multimers and disulfide-linked oligomers and also associates with other otoconial proteins including and Otoconin-90 (also known as PLA2G2A, PLA2L, and phospholipase A2 homolog) and Cerebellin-1. It is extensively glycosylated and has multiple hydroxylated proline residues in the collagenous regions.

Research Area: Signal Transduction,